Molecular Mechanisms Linking Exercise to Cancer Prevention and Treatment
The benefits of exercise training for cancer patients are becoming increasingly evident. Physical exercise has been shown to reduce cancer incidence and inhibit tumor growth. Here we provide the status of the current molecular understanding of the effect of exercise on cancer. We propose that exercise has a role in controlling cancer progression through a direct effect on tumor-intrinsic factors, interplay with whole-body exercise effects, alleviation of cancer-related adverse events, and improvement of anti-cancer treatment efficacy. These findings have wide-ranging societal implications, as this understanding may lead to changes in cancer treatment strategies.
regular exercise in general decreases the risk of cancer and can control tumor growth, and that this effect is unrelated to the specific cancer diagnoses. These tumor growth-inhibitory effects are probably mediated by several different mechanisms, and their individual contributions to the inhibitory effect of exercise may vary in importance across different cancer diagnoses.
Common Design 