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MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles

Several recent studies have portrayed DNA methylation as a new player in the recruitment of transcription factors (TF) within chromatin, highlighting a need to connect TF binding sites (TFBS) with their respective DNA methylation profiles.

DNA methylation patterns within TFBS can be cell specific

for a given TF, different DNA methylation profiles are associated with different DNA binding motifs