Interdigital tissue remodelling in the embryonic limb involves dynamic regulation of the miRNA profiles

Altogether, our study provides the miRNA profile associated with a characteristic process of embryonic tissue remodelling supporting the active and redundant participation of miRNAs in programmed cell death and senescence in a fashion similar to that observed in cancer.

Studies are now in progress to confirm or discard at the functional level the significance of the distinct miRNAs identified in the present expression analysis.