The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs
Transposable elements (TEs) compose about half of the mammalian genome and, as embedded sequences, up to 40% of long noncoding RNA (lncRNA) transcripts. Embedded TEs may represent functional domains within lncRNAs, providing a structured RNA platform for protein interaction.
The diversity of lncRNAs’ activity and function mainly depends on their modular architecture and their physical interactions with proteins.
TEs act as functional modules in lncRNAs
Common Design 