Controlling The Waves Of Dynamic, Far From Equilibrium States: The NF-KB System Of Transcription Regulation
Right from the start, GP graciously warns us (curious readers) to fasten our seat belts and get ready for a thrilling ride that is filled with very insightful but provocative explanations (perhaps a little too technical for some folks):
the cell implements the same functions as complex machines do, and much more.
to do that, you need much greater functional complexity than you need to realize a conventional machine.
dynamic, far from equilibrium systems that can be as successful as a conventional machine, or more, must certainly be incredibly complex and amazing systems, systems that defy everything else that we already know and that we can conceive. They must not only implement their functional purposes, but they must do that by “harnessing” the constantly changing waves of change, of random noise, of improbability.
Please, note that almost a year ago GP wrote this excellent article:
Transcription Regulation: A Miracle Of Engineering
(visited 3,545 times and commented 334 times)
following another very interesting discussion started by PaV a month earlier:
Chromatin Topology: The New (And Latest) Functional Complexity
(visited 3,338 times and commented 241 times)
Before this discussion goes further, I want to share my delight in seeing this article here today and express my deep gratitude to GP for taking time to write it and for leading the discussion that I expect this fascinating topic should provoke.
Common Design 