A ribosome attaches to one end of a strand of messenger RNA and begins traveling down the strand searching for the position where it must begin decoding the genetic message to translate the code into protein. Scientists have known for many years that this “start codon” is the nucleotide triplet AUG. They have also identified 24 initiation factors required for this first step. But many other details remain undefined.
the basic “how does- it-work” questions remain the most inspiring
if eIF1 is like the master switch of protein translation’s initiation phase, what throws the switch?
There are still more nuances of this dance to discover.
