Engineering yeast endosymbionts as a step toward the evolution of mitochondria

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Engineering yeast endosymbionts as a step toward the evolution of mitochondria

Angad P. MehtaLubica SupekovaJian-Hua ChenKersi PestonjamaspPaul WebsterYeonjin KoScott C. HendersonGerry McDermottFrantisek Supek, and Peter G. Schultz

It has been hypothesized that mitochondria evolved from a bacterial ancestor that initially became established in an archaeal host cell as an endosymbiont.

This readily manipulated chimeric system […] should allow us to investigate various aspects of the endosymbiotic theory of mitochondrial evolution.