Post-Turing tissue pattern formation: Advent of mechanochemistry
Chemical and mechanical pattern formation is fundamental during embryogenesis and tissue development. Yet, the underlying molecular and cellular mechanisms are still elusive in many cases.
During embryogenesis, biological tissues gradually increase their complexity by self-organised creation of diverse chemical and mechanical patterns. Detailed mechanisms driving and controlling these patterns are not well understood.
one of the big mysteries in biology: The mechanisms of self-organised pattern formation during embryogenesis.
During embryogenesis or tissue development, various chemical and mechanical patterns emerge in a self-organised way based on relatively simple structures
the knowledge about how chemical patterns are produced, controlled, and how they interact with mechanical patterns is still very unsatisfactory.
these results demonstrate the high capacity of mechanochemical interactions during tissue development—a possibly still underestimated driving force of embryonic pattern formation.
the presented approach may serve as a future basis of enhance interactions of experiments with simulation methods in order to further unravel one of the big mysteries in development: the self-organised generation of patterns and shapes.
Common Design 