Where’s the beef?
Long-term evolution on complex fitness landscapes when mutation is weak
Understanding evolution on complex fitness landscapes is difficult both because of the large dimensionality of sequence space and the stochasticity inherent to population-genetic processes.
Understanding evolutionary dynamics on general fitness landscapes remains an important project for theoretical population genetics
we still lack a general theory that would apply to finite polymorphic populations on complex fitness landscapes, making it difficult to address the types of questions we have considered here in that more realistic context.
Common Design 